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Your DNA Song Ltd

Now you can have your own DNA translated and scored into an unforgettable piece of music MORE INFO

DNA Music Lecture Video by David Deamer, Professor of Chemistry, UC Santa Cruz Wonderfest 2007 - Recorded 10/27/07

Imagine the mRNA to be like a long piece of magnetic recording tape, and the ribosome to be like a tape recorder.
As the tape passes through the playing head of the recorder, it is "read" and converted into music, or other sounds...
When a "tape" of mRNA passes through the "playing head" of a ribosome, the "notes" produced
are amino acids and the pieces of music they make up are proteins.

Godel, Escher, Bach, Douglas Hofstadter comments on similarities between genes and music.

 

Music Samples

  Dance of the Manta Ray

    Commissioned by Scott Moore (Canada)

 

 

Translated into music from the Mitochondrial DNA of a Giant Manta Ray:

Protein Translation: KVWSPQYFLDLHMQVSAFR-ERPNRP-NLIRSWYQAHTKNSP-RLAQPHPQGNSAV
INIAL-A-A-VNQSYKELVNLVPATAVIRVTQINIPRR-G-LETISSI-S-DLIKLSYAL

 

 

Humpback Whale (Megaptera Novaeangliae) Subject #3 - Adagio Cantabile


Mp3 sample of a Humpback Whale's DNA translated into music from DNA VARIATIONS VOL 1
 



You can donate to Greenpeace by purchasing the 'Humpback Whale DNA'
track from Stuart's new album DNA Variations.

Mute swan (Cygnus olor)

    

Listen to a music sample of the DNA of a Swan 

PROTEIN SEQUENCE.: Cygnus olor (Mute swan)

VLSAADKT NVKGVFSK IGGHADDY GAETLERM FIAYPQTK TYFPHFDL

QHGSAQI KAHGKKVA AALVEAVN HIDDIAGA LSKLSDLH AQKLRVD

PVNFKFLG HCFLVVV AIHHPSA LTPEVHAS LDKFLCAV GAVLTAKYR

V I D E O S

DNA Music Lecture Video with David Deamer Professor of Chemistry, UC Santa Cruz


Stuart Mitchell - DNA  V a r i a t i o n s  (Spring - 2008)

Now science and music can allow the genetic sequence of the whale to fund its own survival
All royalties and proceeds collected on behalf of The Humpback Whale DNA music
are re-distributed back into the conservation of these wonderful mammals through the organisation and cooperation of Greenpeace.

 

 



You can donate to Greenpeace by purchasing the 'Humpback Whale DNA'
track from Stuart's new album DNA Variations for £1.99

DNA Variations (2008) Available Spring 2008

A new symphonic work by Stuart Mitchell which expresses the protein patterns/music that exists within the four bases of DNA. The protein sequences of a 70 Million year old T-Rex, a Humpback Whale, an orchestral fugue of the composer's son Lewis's DNA melody entwined with the composer's own DNA, culminating with Gene sequence of TCM-1 Mouse that was ultimately responsible for the cause of Ludwig Van  Beethoven's deafness.

DNA music is simply listening to proteins and is a very direct way to explore their patterns. Like music, proteins are composed of strings of phrases and themes that may repeat themselves both within a protein and across time. New protein texts are written over old ones. Proteins change over time and an ancestral protein can generate a family of descendants in which changes in the original text can result in a subtle refolding into a form that serves different functions than the ancestral form.

 


Beethoven's DNA and an Orchid are expressed in the new works

 

DNA Variations Vol 2 (The Earth) - Stuart Mitchell (2008)

1st Movement : Tyrannosaurus Rex DNA Sequence.

National Geographic News Report :
A Tyrannosaurus rex fossil has yielded what appear to be the only preserved soft tissues ever recovered from a dinosaur. Taken from a 70-million-year-old thighbone, the structures look like the blood vessels, cells, and proteins involved in bone formation.

CO1A1_TYREX Collagen alpha-1(I) chain - Tyrannosaurus Rex
GATGAPGI AGAPGFPG ARGAPGPQ GPAGAPGP KGVQGPPG
PQGPRGAA GPPGATGF PGAAGRGV VGLPGQR
The music sounds dominant and deeply foreboding and also gives the listener 
a true incite into the character and behaviour of these once majestic and
enigmatic rulers of the Earth.

 

Protein fragments were extracted from a 70 million year old bone fossil
and translated into music with incredible rhythmic and melodic results.

 

 

'Scientists write down these amino acid sequences as series of text letters. Clark and her colleagues
assign musical notes to the different values of the amino acids in each sequence.
The result is music in the form of "protein songs".

'If people can understand how the music is produced, he said, they can understand how DNA codes proteins.
Clark said one of the more interesting things demonstrated by the music is the differences and
similarities between the same protein of different species.
While some proteins change very little between species, others, such as beta globin, are quite variable.
Therefore, Clark said, by playing the beta globin song for a human and tuatara, an ancient three-eyed lizard,
people can hear the process of evolution—a variation on a theme that was present
before mammals split from reptiles some 200 million years ago.'

Ross King, a computer scientist at the University of Wales, Aberystwyth and
Mary Anne Clark - Your DNA is a Song : Scientists Use Music to Code Proteins

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Possible Physiological Manifestations Through the DNA Code

Source:
The Infrared Frequencies of DNA Bases, as Science and Art

Susan Alexjander, M.A.


"The trick is to hear the music that is the body.
If we can do so, the meaning of the body can be transformed.
It becomes not a blind, silent, doomed machine
but a glorious composition,
a part of God's oeuvre... 'The Great Tone.'"
Meaning and Medicine, Larry Dossey, M.D.

Again, MATH makes processes visible. It decodes meanings. We can see the self-organizing power of the universe, and because the universe is a community it is constantly communicating. Are the sounds of DNA communicating anything to us?

Sequencia first begins to communicate through its concept, that we can hear the hidden beauty of life. This helps to give us a perspective - to find our place in the "Great Tone." This comes directly out of the ancient Greek definition of education: the purpose of studying science and the natural world is to find our proper place in it, allowing us to fulfill our role in the larger pattern. It is truly "student-centered learning," and the natural world is the primary educator. Art processes which translate directly from nature allow us deeper access into levels of being. And art is of course a celebration.

The second way Sequencia communicates is simply because it is music. This is more than a casual statement. We are attracted, often like moths to a flame, to music. One explanation is that composed music can be seen as a metaphor for life itself.

Music, or organized sound, is just about perfect as a metaphor for life. It is born, goes through a process of evolution and transformation, perhaps repeats itself or creates new avenues of life, and dies. (If you really listen, after it is over you can still hear the sounds continuing). The components of music express a yearning for balance. Energy is gathered together for forward motion, and then is released. Pulses, small ones for frequencies, larger ones for rhythms, and still larger ones for phrasing all act in concert. Relationships are constantly forming and re-forming as new tones, rhythms and events come into the picture and others recede.

Music is the active way we live our lives; the way we like our lives to be. It is the very life process itself. If the music doesn't flow we are deeply disturbed. How long can you tolerate a stuck recording? Bringing physics into the picture adds to this metaphor. Music (literally) mirrors the essence of nature itself in its chaos patterns and mathematics.

The same mathematical formula that characterizes the ebb and flow of music has been discovered to exist widely in nature: the flow of a river, beating of a human heart, the wobbling of the earth's axis. This is more than just simple pulse. The rhythms closely resemble irregular patterns of coastlines, clouds and mountain ranges, and other natural scenery. The brain must, then, on some level perceive its reality as a musical, complex landscape. And turning this around, the music we hear must feel like our earthly home. No wonder we love it.

It is likely that something unusual is being communicated directly through the combinations and ratios of spectral music. The descriptive adjectives one hears most often are: soothing, comfortable, a feeling of spaciousness, expansion. Sequencia is not "new age" or demonstration music, nor was it composed it to "heal" anyone. It was written because that is what a composer does in the world; write music. But after ten years of hearing unique reactions and virtually no complaints from those who hear these strange tunings for the first time, one cannot help but wonder what is going on. Some listeners admit that they never (or hardly ever) listen to music because it 'interferes with what is going on in their heads' or is too invasive. However, they love, even crave, these DNA sounds. About one in every 4 or 5 persons has a deep, almost devotional response. Movement teachers love it, saying their students respond deeply. Would people react in the same way to compositions employing 60 random, microtonal combinations? Who knows? And certainly there are endless styles of tonal arrangement, given the same musical materials to begin with. But these particular DNA ratios, originating in light, are profoundly arresting to the ear. This first wakes up the nervous system, puts it on alert. What follows in sound is then allowed to enter our psyches on a deep level. People report feelings of connectedness, familiarity. "I feel right at home," they say. It is tempting to speculate that the body is recognizing itself, and is communicating this to the psyche.

http://www.oursounduniverse.com/infraredfreq.html

Rosslyn Chapel



A DNA Double Helix structure and Rosslyn's Apprentice Pillar and The Helix Nebula

ROSSLYN MOTET 

DNA music exists within every living organism universally and now we have the technology to
unlock a symphony from within everyone for a better and more aesthetic understanding
of life, ourselves and each other.

For more information: Contact Us Here 


Reference & Sources:

 UniProtKB/Swiss-Prot Protein Knowledgebase

A Protein Primer: A Musical Introduction to Protein Structure

Susan Alexjander M.A - Our Sound Universe

DNA music news source :http://www.cbsnews.com/stories/2003/01/18/tech/main537093.shtml

Ellie Crystal's DNA research - Journey of our DNA

A Physiological Approach to DNA Music

Douglas Hofstadter  Godel, Escher, Bach,

What is Gene Music? http://www.toshima.ne.jp/~edogiku/TextTable/WhatisGM.html

John Dunn - Algorithmic Arts

IUPAC-IUB Joint Commission on Biochemical Nomenclature (JCBN).
Nomenclature and Symbolism for Amino Acids and Peptides. Recommendations 1983.
Eur. J. Biochem. 138:9-37(1984).

See also: http://www.chem.qmw.ac.uk/iupac/AminoAcid/

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Copyright 2007 Stuart Mitchell